Evolution of virulence when transmission occurs before disease

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Evolution of virulence when transmission occurs before disease.

Most models of virulence evolution assume that transmission and virulence are constant during an infection. In many viral (HIV and influenza), bacterial (TB) and prion (BSE and CWD) systems, disease-induced mortality occurs long after the host becomes infectious. Therefore, we constructed a model with two infected classes that differ in transmission rate and virulence in order to understand how...

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ژورنال

عنوان ژورنال: Biology Letters

سال: 2010

ISSN: 1744-9561,1744-957X

DOI: 10.1098/rsbl.2009.1019